Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18122086 | 0.73 | HTR6 (0.43) | HTR6PTGS2TYK2 | |
| SCHEMBL21001663 | 0.71 | KDM4E (0.45) | HTR6PTGS2PDE2ATYK2 | |
| SCHEMBL21033308 | 0.69 | HTR6 (0.41) | HTR6PTGS2TYK2 | |
| SCHEMBL21033150 | 0.66 | HTR6 (0.39) | HTR6PTGS2PDE2ATYK2 | |
| SCHEMBL23047161 | 0.66 | PDE10A (0.44) | HTR6PTGS2 | |
| SCHEMBL8354136 | 0.63 | KDM4E (0.39) | HTR6PTGS2PDE2A | |
| SCHEMBL31001747 | 0.63 | TGFBR1 (0.31) | — | |
| SCHEMBL7456444 | 0.62 | JAK2 (0.36) | HTR6PTGS2PDE2A | |
| SCHEMBL31001778 | 0.61 | TGFBR1 (0.31) | — | |
| SCHEMBL15308500 | 0.60 | ALDH1A1 (0.45) | HTR6PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210371431-A1 | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS | JUBILANT EPISCRIBE LLC | 2021-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210371431-A1 | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS | PRMT5, PRMT1, PRMT3 | HTR6 3187/4885PTGS2 3251/4885PDE2A 654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.