Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | GPR3 | P46089 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25461085 | 0.85 | MAPK10 (0.50) | KDM4EGPR3CYP3A4MAPK10HTT | |
| SCHEMBL29900146 | 0.84 | KDM4E (0.67) | KDM4EGPR3CYP3A4MAPK10HTT | |
| SCHEMBL2407348 | 0.84 | KDM4E (0.67) | KDM4EGPR3CYP3A4HTTLMNA | |
| SCHEMBL31135312 | 0.84 | KDM4E (0.67) | KDM4EGPR3CYP3A4HTTLMNA | |
| SCHEMBL2386455 | 0.84 | KDM4E (0.67) | KDM4EGPR3CYP3A4MAPK10HTT | |
| Phenanthridine SCHEMBL28242096 | 0.82 | KDM4E (0.69) | KDM4EGPR3CYP3A4MAPK10HTT | |
| Phenanthridine SCHEMBL8666 | 0.81 | GPR3 (1.00) | KDM4EGPR3CYP3A4LMNANPC1 | |
| Phenanthridine SCHEMBL9106884 | 0.81 | GPR3 (1.00) | KDM4EGPR3CYP3A4LMNANPC1 | |
| Phenanthridine SCHEMBL30914262 | 0.81 | GPR3 (1.00) | KDM4EGPR3CYP3A4LMNANPC1 | |
| Phenanthridine SCHEMBL30823553 | 0.81 | GPR3 (1.00) | KDM4EGPR3CYP3A4LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357188-A1 | PHENANTHRENE ORGANIC COMPOUND AND USE THEREOF | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-11-09 | — | — | US | disclosed |
| US-20230357188-A1 | PHENANTHRENE ORGANIC COMPOUND AND USE THEREOF | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-11-09 | — | — | US | disclosed |
| US-20230151020-A1 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-05-18 | — | — | US | disclosed |
| US-20230151020-A1 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-05-18 | — | — | US | disclosed |
| US-10472380-B2 | Platinum compounds having a heterocycle ligand, nanoparticles, and uses thereof | PLACON THERAPEUTICS, INC. (US) | 2019-11-12 | — | — | US | disclosed |
| US-20170349615-A1 | PLATINUM COMPOUNDS HAVING A HETEROCYCLE LIGAND, NANOPARTICLES, AND USES THEREOF | XLINK THERAPEUTICS, INC. | 2017-12-07 | — | — | US | disclosed |
| US-9780310-B2 | Heterocyclic compound for organic electroluminescent device and its application | TOSOH CORPORATION (JP) | 2017-10-03 | — | — | US | disclosed |
| US-9771387-B2 | Platinum compounds having a heterocycle ligand, nanoparticles, and uses thereof | PLACON THERAPEUTICS (US) | 2017-09-26 | — | — | US | disclosed |
| US-20160152646-A1 | PLATINUM COMPOUNDS HAVING A HETEROCYCLE LIGAND, NANOPARTICLES, AND USES THEREOF | XLINK THERAPEUTICS, INC. | 2016-06-02 | — | — | US | disclosed |
| US-20160056388-A1 | HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ITS APPLICATION | TOSOH CORPORATION (JP) | 2016-02-25 | — | — | US | disclosed |
| WO-2014043243-A2 | PLATINUM COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | BLEND THERAPEUTICS (US) | 2014-03-20 | — | — | WO | disclosed |
| WO-2011105700-A1 | NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2011-09-01 | — | — | WO | disclosed |
| US-20080009498-A1 | Phosphodiesterase inhibitors and nitric oxide donors, compositions and methods of use | NITROMED, INC. (US) | 2008-01-10 | — | — | US | disclosed |
| US-20040087591-A1 | Phosphodiesterase inhibitors and nitric oxide donors, compositions and methods of use | GARVEY DAVID S (US) | 2004-05-06 | — | — | US | disclosed |
| EP-0988302-B1 | BENZONAPHTHYRIDINES | ALTANA PHARMA AG (DE) | 2003-02-19 | — | — | EP | disclosed |
| US-RE37234-E1 | Nitrosated and nitrosylated phosphodiestrase inhibitor compounds, compositions and their uses | NITROMED, INC. | 2001-06-19 | — | — | US | disclosed |
| US-6221881-B1 | TREATING A SEXUAL DYSFUNCTION | NITROMED, INC. | 2001-04-24 | — | — | US | disclosed |
| US-6197778-B1 | THERAPY FOR SEXUAL DISORDERS | NITROMED, INC. | 2001-03-06 | — | — | US | disclosed |
| US-6172068-B1 | SEXUAL DISORDERS | NITROMED, INC. | 2001-01-09 | — | — | US | disclosed |
| US-6172060-B1 | THERAPY FOR SEXUAL DISORDERS | NITROMED, INC. | 2001-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349615-A1 | PLATINUM COMPOUNDS HAVING A HETEROCYCLE LIGAND, NANOPARTICLES, AND USES THEREOF | TP53, PDCD1LG2, IDH1 | KDM4E 4074/4885GPR3 2899/4885CYP3A4 3327/4885 |
| US-20160152646-A1 | PLATINUM COMPOUNDS HAVING A HETEROCYCLE LIGAND, NANOPARTICLES, AND USES THEREOF | TP53, PDCD1LG2, IDH1 | KDM4E 4074/4885GPR3 2899/4885CYP3A4 3327/4885 |
| US-20160056388-A1 | HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ITS APPLICATION | AOC2, AZI2, KCNH2 | KDM4E 995/4885GPR3 3295/4885CYP3A4 1069/4885 |
| US-20230357188-A1 | PHENANTHRENE ORGANIC COMPOUND AND USE THEREOF | AHR, ORAI3, WNT3 | KDM4E 3942/4885GPR3 8/4885CYP3A4 542/4885 |
| US-20080009498-A1 | Phosphodiesterase inhibitors and nitric oxide donors, compositions and methods of use | PDE3A, PDE3B, PDE2A | KDM4E 1851/4885GPR3 356/4885CYP3A4 745/4885 |
| US-20040087591-A1 | Phosphodiesterase inhibitors and nitric oxide donors, compositions and methods of use | PDE3A, PDE3B, PDE5A | KDM4E 4598/4885GPR3 103/4885CYP3A4 1306/4885 |
| US-20230151020-A1 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | OCIAD1, OCIAD2, EHD1 | KDM4E 2555/4885GPR3 4426/4885CYP3A4 949/4885 |
| US-10472380-B2 | Platinum compounds having a heterocycle ligand, nanoparticles, and uses thereof | TP53, PDCD1LG2, IDH1 | KDM4E 4074/4885GPR3 2899/4885CYP3A4 3327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.