SCHEMBL2407435

SCHEMBL2407435

[c]1ccc2c(c1)-c1cccc3c[c]cc-2c13

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
TSHR P16473 3/20 0.46
MAPK1 P28482 3/20 0.46
HSD17B10 Q99714 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ATM Q13315 1/20 0.46
CASP1 P29466 3/20 0.38
CASP7 P55210 2/20 0.38
CYP3A4 P08684 1/20 0.38
PABPC1 P11940 1/20 0.38
DNMT1 P26358 1/20 0.38
HPGD P15428 2/20 0.38
HIF1A Q16665 2/20 0.38
TP53 P04637 1/20 0.38
CES2 O00748 1/20 0.34
BCHE P06276 1/20 0.34
CES1 P23141 1/20 0.34
MCL1 Q07820 1/20 0.34
KLK7 P49862 1/20 0.33
TYMS P04818 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2413791 1.00 ALDH1A1 (0.46) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL578457 0.90 ALDH1A1 (0.58) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL1232029 0.88 ALDH1A1 (0.61) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL2411569 0.77 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL1350657 0.76 MEN1 (0.36) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL28981543 0.74 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL2409720 0.74 ALDH1A1 (0.39) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL2413530 0.74 ALDH1A1 (0.34) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL15062680 0.73
SCHEMBL15062522 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11706981-B2 Organic light emitting device and compounds for use in same IDEMITSU KOSAN CO., LTD. (JP) 2023-07-18 US disclosed
US-11616201-B2 Specific ladder type compounds for organic light emitting devices IDEMITSU KOSAN CO., LTD. (JP) 2023-03-28 US disclosed
US-20220109115-A1 POLYCYCLIC COMPOUND, AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE POLYCYCLIC COMPOUND IDEMITSU KOSAN CO.,LTD. (JP) 2022-04-07 US disclosed
US-11264576-B2 Specifically substituted ladder type compounds for organic light emitting devices IDEMITSU KOSAN CO., LTD. (JP) 2022-03-01 US disclosed
CN-112888693-A Polycyclic compound and organic electroluminescent device comprising same 出光兴产株式会社 2021-06-01 CN disclosed
US-20200381628-A1 SPECIFIC LADDER TYPE COMPOUNDS FOR ORGANIC LIGHT EMITTING DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2020-12-03 US disclosed
US-20200227652-A1 ORGANIC LIGHT EMITTING DEVICE AND COMPOUNDS FOR USE IN SAME IDEMITSU KOSAN CO., LTD. (JP) 2020-07-16 US disclosed
EP-3680242-A1 ORGANIC LIGHT EMITTING DEVICE AND COMPOUNDS FOR USE IN SAME Idemitsu Kosan Co., Ltd. (JP) 2020-07-15 EP disclosed
EP-3670517-A1 POLYCYCLIC COMPOUND, COMPOSITION AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE POLYCYCLIC COMPOUND OR THE COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2020-06-24 EP disclosed
EP-3418285-B1 COMPOSITION COMPRISING A SUBSTITUTED IR COMPLEX AND A PHENYLQUINAZOLINE BRIDGED WITH A HETEROATOM IDEMITSU KOSAN CO (JP) 2020-05-06 EP disclosed
EP-3604477-A1 POLYCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE Idemitsu Kosan Co., Ltd. (JP) 2020-02-05 EP disclosed
EP-3569605-A1 NOVEL ELECTROLUMINESCENT METAL COMPLEXES AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2019-11-20 EP disclosed
WO-2019155363-A1 BENZO-IMIDAZOINDOLIZINE DERIVATIVE, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL USING THE SAME, AND ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-08-15 WO disclosed
EP-3524607-A1 BENZO-IMIDAZOINDOLIZINE DERIVATIVE, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL USING THE SAME, AND ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2019-08-14 EP disclosed
EP-3466954-A1 FUSED PHENYLQUINAZOLINES BRIDGED WITH A HETEROATOM Idemitsu Kosan Co., Ltd. (JP) 2019-04-10 EP disclosed
EP-3418285-A1 COMPOSITION COMPRISING A SUBSTITUTED IR COMPLEX AND A PHENYLQUINAZOLINE BRIDGED WITH A HETEROATOM Idemitsu Kosan Co., Ltd. (JP) 2018-12-26 EP disclosed
WO-2018154501-A1 SPECIFIC LADDER TYPE COMPOUNDS FOR ORGANIC LIGHT EMITTING DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2018-08-30 WO disclosed
WO-2018124313-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS FOR ORGANIC LIGHT EMITTING DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2018-07-05 WO disclosed
WO-2018116152-A1 SPECIFICALLY SUBSTITUTED LADDER TYPE COMPOUNDS FOR ORGANIC LIGHT EMITTING DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2018-06-28 WO disclosed
WO-2011105700-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-09-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11264576-B2 Specifically substituted ladder type compounds for organic light emitting devices APOL1, LOXL1, EML4 ALDH1A1 13/4885TSHR 4838/4885MAPK1 103/4885
US-11706981-B2 Organic light emitting device and compounds for use in same SLCO4C1, XPO6, ERCC1 ALDH1A1 499/4885TSHR 3746/4885MAPK1 2636/4885
US-11616201-B2 Specific ladder type compounds for organic light emitting devices APOL1, HMGB2, LOXL1 ALDH1A1 101/4885TSHR 2474/4885MAPK1 348/4885
US-20220109115-A1 POLYCYCLIC COMPOUND, AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE POLYCYCLIC COMPOUND ODC1, OTC, PKD1 ALDH1A1 718/4885TSHR 4170/4885MAPK1 1318/4885
US-20200381628-A1 SPECIFIC LADDER TYPE COMPOUNDS FOR ORGANIC LIGHT EMITTING DEVICES APOL1, HMGB2, LOXL1 ALDH1A1 101/4885TSHR 2474/4885MAPK1 348/4885
US-20200227652-A1 ORGANIC LIGHT EMITTING DEVICE AND COMPOUNDS FOR USE IN SAME SLCO4C1, XPO6, ERCC1 ALDH1A1 499/4885TSHR 3746/4885MAPK1 2636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.