SCHEMBL24079154

SCHEMBL24079154

Cc1cnc(-c2ccc(C)c(-c3ccccc3C)c2)cc1CC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.36
FEN1 P39748 1/20 0.36
CYP1A2 P05177 10/20 0.34
CYP2C19 P33261 8/20 0.34
CYP2D6 P10635 7/20 0.34
CLK4 Q9HAZ1 6/20 0.34
ALOX15 P16050 2/20 0.34
HSD17B10 Q99714 2/20 0.34
NPC1 O15118 1/20 0.34
LCK P06239 1/20 0.34
KDR P35968 1/20 0.34
JAK3 P52333 1/20 0.34
MAPK14 Q16539 1/20 0.34
CYP3A4 P08684 7/20 0.34
TSHR P16473 5/20 0.34
TP53 P04637 2/20 0.34
HIF1A Q16665 2/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23561746 0.90 LDHA (0.37) ALOX5APFEN1CYP1A2CYP2C19NPC1
SCHEMBL24079155 0.87 HTR7 (0.40) ALOX5APFEN1LCKKDRJAK3
SCHEMBL22134621 0.85 LRRK2 (0.32) TP53MEN1KMT2A
SCHEMBL25983061 0.85 CYP1A2 (0.35) ALOX5APFEN1CYP1A2CYP2C19CYP2D6
SCHEMBL18730286 0.82 LDHA (0.46) NPC1KDRCYP3A4MEN1KMT2A
SCHEMBL24066435 0.82 LDHA (0.37) ALOX5APFEN1CYP1A2CYP2C19NPC1
SCHEMBL24079157 0.80 LDHA (0.39) NPC1KDRCYP3A4CYP11B1CYP11B2
SCHEMBL24079159 0.79 PDCD1 (0.37) CYP1A2CYP2C19CYP2D6CLK4ALOX15
SCHEMBL24066580 0.79 LDHA (0.40) ALOX5APFEN1CYP1A2CYP2C19NPC1
SCHEMBL18729458 0.77 CYP1A2 (0.45) ALOX5APFEN1CYP1A2CYP2C19CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11725021-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-15 US disclosed
EP-3730506-B1 USE OF A HETEROLEPTIC COMPOUND AS AN EMITTER IN AN OLED UNIVERSAL DISPLAY CORP (US) 2021-12-15 EP disclosed
US-11192910-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11725021-B2 Organic electroluminescent materials and devices NCL, OCIAD2, OCIAD1 ALOX5AP 1270/4885FEN1 2848/4885CYP1A2 891/4885
US-11192910-B2 Organic electroluminescent materials and devices L1CAM, LMNB2, LMNB1 ALOX5AP 2576/4885FEN1 2707/4885CYP1A2 1731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.