SCHEMBL24079159

SCHEMBL24079159

Cc1ccccc1-c1cc(-c2cc(CC(C)(C)C)ccn2)ccc1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.37
CD274 Q9NZQ7 1/20 0.37
LOXL2 Q9Y4K0 2/20 0.36
PLA2G7 Q13093 2/20 0.36
CYP1A2 P05177 4/20 0.35
CYP2C19 P33261 4/20 0.35
CLK4 Q9HAZ1 3/20 0.35
CYP2D6 P10635 3/20 0.35
TSHR P16473 2/20 0.35
MAPK1 P28482 2/20 0.35
TP53 P04637 1/20 0.35
HIF1A Q16665 1/20 0.35
TGFBR1 P36897 1/20 0.35
IRAK4 Q9NWZ3 1/20 0.35
FFAR1 O14842 1/20 0.34
ALOX15 P16050 2/20 0.34
HSD17B10 Q99714 1/20 0.34
CYP3A4 P08684 2/20 0.34
SHMT1 P34896 1/20 0.34
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22134626 0.90 PDCD1 (0.42) PDCD1CD274LOXL2CYP1A2CYP2C19
SCHEMBL24079158 0.90 TGFBR1 (0.40) PDCD1CD274CYP1A2CYP2C19CLK4
SCHEMBL23879666 0.87 HTR7 (0.43) PDCD1CD274LOXL2TGFBR1FFAR1
SCHEMBL12866764 0.86 FFAR1 (0.43) PDCD1CD274CYP1A2CYP2C19CLK4
SCHEMBL24079154 0.79 ALOX5AP (0.36) PLA2G7CYP1A2CYP2C19CLK4CYP2D6
SCHEMBL9975654 0.78 ASIC3 (0.53) PDCD1CD274LOXL2FFAR1SHMT1
SCHEMBL18643799 0.77 TGFBR1 (0.46) PDCD1CD274CYP1A2CYP2C19CLK4
SCHEMBL26172508 0.77 LOXL2 (0.41) LOXL2TGFBR1ALDH1A1ASIC3NPC1
SCHEMBL18643801 0.76 TGFBR1 (0.45) PDCD1CD274CYP1A2CYP2C19CLK4
SCHEMBL22134624 0.76 ASIC3 (0.44) PDCD1CD274LOXL2SHMT1ASIC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11725021-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-15 US disclosed
US-11192910-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11725021-B2 Organic electroluminescent materials and devices NCL, OCIAD2, OCIAD1 PDCD1 1058/4885CD274 772/4885LOXL2 23/4885
US-11192910-B2 Organic electroluminescent materials and devices L1CAM, LMNB2, LMNB1 PDCD1 3643/4885CD274 872/4885LOXL2 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.