SCHEMBL24079157

SCHEMBL24079157

Cc1cnc(-c2cccc(-c3ccccc3)c2)cc1CC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.39
KMO O15229 1/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
CYP11B1 P15538 3/20 0.37
CYP11B2 P19099 3/20 0.37
COMT P21964 1/20 0.35
CYP3A4 P08684 1/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
PDGFRB P09619 1/20 0.35
KDR P35968 1/20 0.35
FLT3 P36888 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CTSA P10619 1/20 0.34
MAP4K4 O95819 1/20 0.34
IDO1 P14902 1/20 0.33
TDO2 P48775 1/20 0.33
PSMB5 P28074 1/20 0.33
RIPK1 Q13546 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18730286 0.91 LDHA (0.46) LDHACYP11B1CYP11B2CYP3A4NPC1
SCHEMBL24183270 0.89 LDHA (0.42) LDHAKMOLOXL2CYP11B1CYP11B2
SCHEMBL24079155 0.88 HTR7 (0.40) LDHACYP11B1CYP11B2KDRCTSA
SCHEMBL23561746 0.85 LDHA (0.37) LDHACYP11B1CYP11B2CYP3A4NPC1
SCHEMBL26316040 0.81 LDHA (0.38) LDHACYP11B1CYP11B2CYP3A4NPC1
SCHEMBL20980466 0.80 IRAK4 (0.32) NPC1RAB9AKDRSMN1; SMN2
SCHEMBL24079154 0.80 ALOX5AP (0.36) CYP11B1CYP11B2CYP3A4NPC1KDR
SCHEMBL18730751 0.79 LDHA (0.50) LDHACYP11B1CYP11B2CYP3A4NPC1
SCHEMBL18729686 0.79 LDHA (0.41) LDHACYP11B1CYP11B2CYP3A4NPC1
SCHEMBL13834213 0.78 LDHA (0.51) LDHAKMOLOXL2COMTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11192910-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11192910-B2 Organic electroluminescent materials and devices L1CAM, LMNB2, LMNB1 LDHA 7/4885KMO 3701/4885LOXL2 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.