SCHEMBL18730751

SCHEMBL18730751

Cc1cc(-c2ccccc2)ncc1CC(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.50
CYP11B1 P15538 7/20 0.43
CYP11B2 P19099 7/20 0.43
RAB9A P51151 3/20 0.41
NPC1 O15118 3/20 0.41
PDGFRB P09619 1/20 0.41
KDR P35968 1/20 0.41
FLT3 P36888 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP3A4 P08684 2/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.40
ASIC3 Q9UHC3 1/20 0.39
IDO1 P14902 1/20 0.36
TDO2 P48775 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24183270 0.91 LDHA (0.42) LDHACYP11B1CYP11B2RAB9ANPC1
SCHEMBL24066580 0.87 LDHA (0.40) LDHACYP11B1CYP11B2RAB9ANPC1
SCHEMBL22549187 0.87 KDM1A (0.38) LDHACYP11B1CYP11B2RAB9ANPC1
SCHEMBL18730286 0.87 LDHA (0.46) LDHACYP11B1CYP11B2RAB9ANPC1
SCHEMBL18729686 0.87 LDHA (0.41) LDHACYP11B1CYP11B2RAB9ANPC1
SCHEMBL25444864 0.86 LDHA (0.40) LDHACYP11B1CYP11B2RAB9ANPC1
SCHEMBL25984037 0.84 HTR7 (0.40) LDHACYP11B1CYP11B2KDR
SCHEMBL20782165 0.83 NPC1 (0.41) LDHACYP11B1CYP11B2RAB9ANPC1
SCHEMBL19373371 0.83 CYP1A2 (0.42) RAB9ANPC1SMN1; SMN2CYP3A4MEN1
SCHEMBL18729640 0.81 LDHA (0.58) LDHACYP11B1CYP11B2RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 US disclosed
US-20230312627-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-10-05 US disclosed
US-20230303601-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
US-20230250118-A1 ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-08-10 US disclosed
US-20210399236-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-12-23 US disclosed
US-10033002-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-07-24 US disclosed
US-20170263872-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-09-14 US disclosed
EP-3159350-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2017-04-26 EP disclosed
EP-3001480-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2017-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303601-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MGLL, SELENOI, APOL1 LDHA 1714/4885CYP11B1 3748/4885CYP11B2 3840/4885
US-20230312627-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, CTCF, DNMT1 LDHA 1959/4885CYP11B1 2738/4885CYP11B2 2770/4885
US-10033002-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, ALKBH2 LDHA 2560/4885CYP11B1 3312/4885CYP11B2 2806/4885
US-20230250118-A1 ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF CRY1, LEF1, PIEZO1 LDHA 314/4885CYP11B1 3783/4885CYP11B2 4211/4885
US-20210399236-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OTC LDHA 539/4885CYP11B1 1467/4885CYP11B2 1201/4885
US-20170263872-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ALKBH2 LDHA 2560/4885CYP11B1 3312/4885CYP11B2 2806/4885
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, L1CAM, OPRM1 LDHA 1161/4885CYP11B1 2335/4885CYP11B2 2440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.