Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 14/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.48 |
| ▸ | USP2 | O75604 | 5/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.46 |
| ▸ | CASP1 | P29466 | 6/20 | 0.46 |
| ▸ | CASP7 | P55210 | 6/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2410186 | 0.90 | MAPT (0.42) | CYP1A2ALDH1A1HSD17B10USP2CASP1 | |
| SCHEMBL2408774 | 0.89 | HPGD (0.41) | CYP1A2ALDH1A1HSD17B10USP2CASP1 | |
| SCHEMBL2408398 | 0.88 | PTPN11 (0.41) | RPS6KA3PIK3CAMTORPIK3CGCYP1A2 | |
| SCHEMBL2411816 | 0.82 | RPS6KA3 (0.55) | RPS6KA3CYP1A2ALDH1A1HSD17B10USP2 | |
| SCHEMBL2410524 | 0.78 | CFTR (0.47) | RPS6KA3PIK3CAMTORPOLB | |
| SCHEMBL2409198 | 0.78 | HDAC6 (0.52) | RPS6KA3PIK3CAMTORALDH1A1HSD17B10 | |
| SCHEMBL2533233 | 0.77 | RIPK1 (0.37) | RPS6KA3PIK3CAMTORHPGD | |
| SCHEMBL2533237 | 0.77 | MKNK1 (0.36) | RPS6KA3PIK3CAMTORPOLBHPGD | |
| SCHEMBL2408806 | 0.76 | CYP1A2 (0.44) | RPS6KA3CYP1A2ALDH1A1HSD17B10USP2 | |
| SCHEMBL2407291 | 0.76 | CFTR (0.46) | RPS6KA3CYP1A2ALDH1A1HSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106168-A1 | PURINE COMPOUNDS FOR TREATING AUTOIMMUNE AND DEMYELINATING DISEASES | DCAM PHARMA INC (US) | 2011-09-01 | — | — | WO | claimed |
| WO-2011106168-A1 | PURINE COMPOUNDS FOR TREATING AUTOIMMUNE AND DEMYELINATING DISEASES | DCAM PHARMA INC (US) | 2011-09-01 | — | — | WO | disclosed |
| WO-2011106168-A1 | PURINE COMPOUNDS FOR TREATING AUTOIMMUNE AND DEMYELINATING DISEASES | DCAM PHARMA INC (US) | 2011-09-01 | — | — | WO | disclosed |