Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2410524 | 0.85 | CFTR (0.47) | HDAC6MAPTCFTRRIPK1RIPK3 | |
| SCHEMBL17802582 | 0.84 | CFTR (0.54) | HDAC6MAPTCFTRTP53RPS6KA3 | |
| SCHEMBL2408806 | 0.83 | CYP1A2 (0.44) | MAPTRIPK1RIPK3TP53RPS6KA3 | |
| SCHEMBL2410186 | 0.80 | MAPT (0.42) | HDAC6MAPTRIPK1RIPK3ALDH1A1 | |
| SCHEMBL2408774 | 0.79 | HPGD (0.41) | HDAC6MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL4978113 | 0.78 | XDH (0.48) | HDAC6MAPTRPS6KA3FGFR1KDM4E | |
| SCHEMBL2408339 | 0.78 | RPS6KA3 (0.48) | RPS6KA3ALDH1A1HPGDHSD17B10PIK3CA | |
| SCHEMBL2408398 | 0.78 | PTPN11 (0.41) | MAPTRIPK1RIPK3TP53RPS6KA3 | |
| SCHEMBL2533237 | 0.75 | MKNK1 (0.36) | MAPTRIPK1RIPK3TP53RPS6KA3 | |
| SCHEMBL2533233 | 0.75 | RIPK1 (0.37) | MAPTRIPK1RIPK3TP53RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106168-A1 | PURINE COMPOUNDS FOR TREATING AUTOIMMUNE AND DEMYELINATING DISEASES | DCAM PHARMA INC (US) | 2011-09-01 | — | — | WO | claimed |
| WO-2011106168-A1 | PURINE COMPOUNDS FOR TREATING AUTOIMMUNE AND DEMYELINATING DISEASES | DCAM PHARMA INC (US) | 2011-09-01 | — | — | WO | disclosed |