Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411398 | 0.91 | SLC40A1 (0.31) | — | |
| SCHEMBL2410111 | 0.91 | DHODH (0.30) | — | |
| SCHEMBL2410511 | 0.88 | ABCC9 (0.33) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL4570000 | 0.88 | MMP2 (0.36) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL2412351 | 0.86 | MET (0.40) | NFE2L2MMP2MMP9MMP8MMP13 | |
| SCHEMBL2191180 | 0.86 | MMP2 (0.36) | NFE2L2MMP2MMP9MMP8MMP13 | |
| SCHEMBL2194308 | 0.86 | MMP9 (0.37) | NFE2L2MMP2MMP9MMP8MMP13 | |
| SCHEMBL2192366 | 0.84 | DCTPP1 (0.31) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL2197222 | 0.84 | — | — | |
| SCHEMBL2194706 | 0.84 | GRM4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |