Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.34 |
| ▸ | IDE | P14735 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1580872 | 0.86 | HTR6 (0.40) | HTR6IDEDRD2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL2413054 | 0.86 | HTR6 (0.39) | HTR6IDEDRD2HTR2AHTR2C | |
| SCHEMBL4418226 | 0.82 | HTR6 (0.35) | HTR6IDEPTGDR2DRD2HTR2A | |
| SCHEMBL5002522 | 0.82 | IDE (0.38) | HTR6IDEPTGDR2NFE2L2 | |
| SCHEMBL4425473 | 0.81 | HTR6 (0.33) | HTR6PLCG1DRD2GRM5 | |
| SCHEMBL2409871 | 0.80 | PTGDR2 (0.33) | HTR6IDEPTGDR2PLCG1HTR2A | |
| SCHEMBL2409873 | 0.80 | HTR6 (0.34) | HTR6PTGDR2KAT8PLCG1HTR2A | |
| SCHEMBL4566581 | 0.79 | PPME1 (0.36) | HTR6PTGDR2PLCG1 | |
| SCHEMBL1580530 | 0.79 | GLO1 (0.38) | HTR6 | |
| SCHEMBL2409876 | 0.79 | HTR6 (0.34) | HTR6IDEPTGDR2PLCG1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |