Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPME1 | Q9Y570 | 3/20 | 0.36 |
| ▸ | RORC | P51449 | 6/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411862 | 0.85 | RORC (0.36) | PPME1RORCHTR6NR3C1NR1H3 | |
| SCHEMBL4563370 | 0.83 | HTR6 (0.37) | PPME1RORCHTR6NR3C1NR1H3 | |
| SCHEMBL2412057 | 0.81 | PPME1 (0.34) | PPME1RORCHTR6NR3C1NR1H3 | |
| SCHEMBL1580530 | 0.81 | GLO1 (0.38) | PPME1HTR6NR3C1KAT6A | |
| Hydrochloric Acid SCHEMBL2409926 | 0.80 | NR3C1 (0.37) | PPME1HTR6NR3C1KAT6A | |
| SCHEMBL4566599 | 0.80 | RXFP1 (0.35) | HTR6PTGDR2 | |
| SCHEMBL4566627 | 0.80 | ABCC9 (0.33) | RORCHTR6 | |
| SCHEMBL2409288 | 0.79 | HTR6 (0.34) | HTR6PLCG1PTGDR2 | |
| SCHEMBL4569945 | 0.79 | ALDH1A1 (0.36) | RORCAOC3NR1H3PTGDR2 | |
| SCHEMBL2412055 | 0.79 | PPME1 (0.34) | PPME1RORCHTR6NR3C1KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |