Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411857 | 0.93 | NR3C1 (0.36) | PLCG1 | |
| SCHEMBL2409994 | 0.92 | PLCG1 (0.33) | PLCG1 | |
| SCHEMBL4419026 | 0.92 | MET (0.40) | HTR6PLCG1DRD2 | |
| SCHEMBL2408490 | 0.90 | HTR6 (0.35) | HTR6DRD2 | |
| SCHEMBL2410874 | 0.88 | NFE2L2 (0.35) | HTR6DRD2 | |
| SCHEMBL2408730 | 0.85 | NR3C1 (0.35) | GRM5 | |
| Hydrochloric Acid SCHEMBL4421014 | 0.85 | HTR6 (0.34) | HTR6DRD2 | |
| SCHEMBL4425656 | 0.83 | MET (0.39) | — | |
| SCHEMBL2409288 | 0.81 | HTR6 (0.34) | HTR6PLCG1DRD2GRM5 | |
| SCHEMBL2410027 | 0.81 | NTRK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |