Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CTSS | P25774 | 5/20 | 0.36 |
| ▸ | CTSL | P07711 | 4/20 | 0.36 |
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23279563 | 0.91 | CTSB (0.39) | CTSBALDH1A1CTSSCTSLCTSK | |
| SCHEMBL23279588 | 0.85 | ALDH1A1 (0.40) | CTSBALDH1A1CTSSCTSLCTSK | |
| SCHEMBL19245063 | 0.84 | CTSB (0.48) | CTSBALDH1A1CTSSCTSLCTSK | |
| SCHEMBL18248065 | 0.83 | MMP13 (0.38) | CTSBALDH1A1CTSSCTSLCTSK | |
| SCHEMBL24093690 | 0.83 | MMP13 (0.38) | CTSBALDH1A1CTSSCTSLCTSK | |
| SCHEMBL18256297 | 0.83 | MMP13 (0.38) | CTSBALDH1A1CTSSCTSLCTSK | |
| SCHEMBL26033123 | 0.80 | CTSB (0.43) | CTSBALDH1A1CTSSCTSLCTSK | |
| SCHEMBL18256483 | 0.78 | CTSS (0.42) | CTSBALDH1A1CTSSCTSLCTSK | |
| SCHEMBL24093774 | 0.75 | — | — | |
| SCHEMBL22502801 | 0.74 | CTSK (0.38) | CTSBALDH1A1CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922639-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-12-15 | — | — | EP | disclosed |