Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4413099 | 0.94 | RECQL (0.33) | POLBRECQLHTR6 | |
| SCHEMBL2414742 | 0.90 | PKM (0.35) | PTGDR2CCKARPKMHTR6 | |
| SCHEMBL2408624 | 0.90 | L3MBTL1 (0.33) | PTGDR2CCKAR | |
| SCHEMBL2418769 | 0.90 | HTR6 (0.37) | PTGDR2PKMHTR6 | |
| SCHEMBL2412879 | 0.89 | PTGDR2 (0.43) | PTGDR2CCKARHTR6 | |
| SCHEMBL2415727 | 0.88 | CHRM5 (0.37) | PTGDR2CCKARHTR6 | |
| SCHEMBL2412446 | 0.87 | POLB (0.37) | POLBPTGDR2CCKARDHODHRECQL | |
| SCHEMBL2415547 | 0.86 | PPME1 (0.35) | PTGDR2HTR6 | |
| SCHEMBL2412424 | 0.85 | PTGDR2 (0.39) | PTGDR2CCKAR | |
| SCHEMBL1278112 | 0.85 | PTGER2 (0.36) | PTGDR2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |