Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24094032 | 0.75 | MEN1 (0.31) | — | |
| SCHEMBL24094059 | 0.72 | ALDH1A1 (0.33) | ALDH1A1TP53HSP90AA1CYP3A4G6PD | |
| SCHEMBL24094045 | 0.70 | ALDH1A1 (0.30) | ALDH1A1GPR84 | |
| SCHEMBL24094097 | 0.70 | ALDH1A1 (0.30) | ALDH1A1GPR84 | |
| SCHEMBL25015171 | 0.67 | BRPF1 (0.33) | ALDH1A1 | |
| SCHEMBL19980344 | 0.67 | NPY2R (0.40) | CYP3A4CYP2D6 | |
| SCHEMBL24094025 | 0.66 | ICMT (0.31) | — | |
| SCHEMBL18635207 | 0.66 | SKP2 (0.32) | ALDH1A1 | |
| SCHEMBL21776545 | 0.64 | PDE4A (0.33) | ALDH1A1 | |
| SCHEMBL12882382 | 0.63 | HPGD (0.46) | ALDH1A1TP53CYP3A4HPGDHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526219-B1 | BICYCLIC PYRIDONE LACTAMS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2021-12-15 | — | — | EP | disclosed |