Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20095566 | 0.85 | GRIA2 (0.33) | — | |
| SCHEMBL24094045 | 0.84 | ALDH1A1 (0.30) | — | |
| SCHEMBL24094081 | 0.82 | SLC6A2 (0.30) | — | |
| SCHEMBL24094097 | 0.76 | ALDH1A1 (0.30) | — | |
| SCHEMBL19980400 | 0.70 | MPO (0.40) | ICMT | |
| SCHEMBL19980344 | 0.68 | NPY2R (0.40) | — | |
| SCHEMBL20344678 | 0.68 | ESR1 (0.38) | — | |
| SCHEMBL24094048 | 0.67 | GRIA2 (0.31) | — | |
| SCHEMBL24094073 | 0.66 | ALDH1A1 (0.33) | — | |
| SCHEMBL21486477 | 0.62 | IDO1 (0.36) | ICMTHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526219-B1 | BICYCLIC PYRIDONE LACTAMS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2021-12-15 | — | — | EP | disclosed |