Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24094097 | 0.89 | ALDH1A1 (0.30) | ALDH1A1GAAERAP1GPR84 | |
| SCHEMBL24094025 | 0.84 | ICMT (0.31) | — | |
| SCHEMBL20095566 | 0.78 | GRIA2 (0.33) | — | |
| SCHEMBL19980400 | 0.71 | MPO (0.40) | — | |
| SCHEMBL24094073 | 0.70 | ALDH1A1 (0.33) | ALDH1A1GPR84 | |
| SCHEMBL19980344 | 0.69 | NPY2R (0.40) | — | |
| SCHEMBL20344678 | 0.69 | ESR1 (0.38) | — | |
| SCHEMBL24094081 | 0.67 | SLC6A2 (0.30) | — | |
| SCHEMBL24094030 | 0.67 | — | — | |
| SCHEMBL25375702 | 0.63 | KDM4E (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526219-B1 | BICYCLIC PYRIDONE LACTAMS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2021-12-15 | — | — | EP | disclosed |