Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4425214 | 0.92 | MAPT (0.33) | — | |
| SCHEMBL2409435 | 0.91 | MET (0.43) | HTR6DRD2MET | |
| SCHEMBL4791733 | 0.88 | PTGS2 (0.30) | — | |
| SCHEMBL4416225 | 0.87 | KAT6A (0.31) | — | |
| SCHEMBL4412054 | 0.87 | MET (0.40) | HTR6HTR2AHTR7DRD2MET | |
| SCHEMBL2408490 | 0.86 | HTR6 (0.35) | HTR6HTR2AHTR2CHTR7DRD2 | |
| SCHEMBL2410132 | 0.82 | MET (0.33) | HTR6METALDH1A1 | |
| SCHEMBL2416547 | 0.81 | HTR6 (0.35) | HTR6HTR2ADRD2ALDH1A1 | |
| SCHEMBL4791657 | 0.80 | FPR1 (0.31) | — | |
| SCHEMBL2410874 | 0.80 | NFE2L2 (0.35) | HTR6HTR2AHTR2CHTR7DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |