Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4421014 | 0.93 | HTR6 (0.34) | HTR6HTR2AHTR2CHTR7DRD2 | |
| SCHEMBL4425656 | 0.93 | MET (0.39) | ALDH1A1MET | |
| SCHEMBL2410874 | 0.92 | NFE2L2 (0.35) | HTR6HTR2AHTR2CHTR7ALDH1A1 | |
| SCHEMBL2410027 | 0.91 | NTRK1 (0.31) | ALDH1A1 | |
| SCHEMBL1832698 | 0.90 | RORC (0.32) | — | |
| SCHEMBL4425473 | 0.90 | HTR6 (0.33) | HTR6DRD2 | |
| SCHEMBL2414854 | 0.89 | KDR (0.34) | MET | |
| SCHEMBL1837632 | 0.87 | PTGS2 (0.30) | — | |
| SCHEMBL1829458 | 0.86 | RORC (0.32) | — | |
| SCHEMBL2412509 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |