Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 4/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.44 |
| ▸ | ITGAL | P20701 | 4/20 | 0.44 |
| ▸ | USP7 | Q93009 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24101163 | 0.81 | TDP1 (0.50) | USP7MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL7551197 | 0.80 | KMT2A (0.62) | USP7MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL24100741 | 0.76 | MEN1 (0.46) | ICAM1USP7MEN1KMT2AL3MBTL1 | |
| SCHEMBL25996836 | 0.76 | ITGB2 (0.43) | ITGB2ICAM1ITGALUSP7MEN1 | |
| SCHEMBL24100835 | 0.75 | USP7 (0.44) | USP7MEN1KMT2AUSP47ALDH1A1 | |
| SCHEMBL4539890 | 0.72 | ALDH1A1 (0.54) | KMT2APOLBCRHBPCRHR2ALDH1A1 | |
| SCHEMBL24100866 | 0.70 | L3MBTL1 (0.43) | MEN1KMT2AL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL8530466 | 0.69 | ALDH1A1 (0.58) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL24101222 | 0.68 | KMT2A (0.46) | MEN1KMT2AL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL3165346 | 0.67 | ITGB2 (0.72) | ITGB2ICAM1ITGALMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233533-A1 | COMPOSITIONS, METHODS OF TREATING AND PREVENTING FUNGAL INFECTIONS, AND METHODS OF INHIBITING PRP8 INTEIN EXPRESSION | HEALTH RESEARCH, INC. (US) | 2023-07-27 | — | — | US | disclosed |
| US-20230233533-A1 | COMPOSITIONS, METHODS OF TREATING AND PREVENTING FUNGAL INFECTIONS, AND METHODS OF INHIBITING PRP8 INTEIN EXPRESSION | HEALTH RESEARCH, INC. (US) | 2023-07-27 | — | — | US | disclosed |
| WO-2021252068-A1 | COMPOSITIONS, METHODS OF TREATING AND PREVENTING FUNGAL INFECTIONS, AND METHODS OF INHIBITING PRP8 INTEIN EXPRESSION | HEALTH RESEARCH, INC. (US) | 2021-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233533-A1 | COMPOSITIONS, METHODS OF TREATING AND PREVENTING FUNGAL INFECTIONS, AND METHODS OF INHIBITING PRP8 INTEIN EXPRESSION | PRPF8, PRPF40A, PRPF19 | ITGB2 3207/4885ICAM1 2928/4885ITGAL 3264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.