Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 12/20 | 0.43 |
| ▸ | USP10 | Q14694 | 1/20 | 0.43 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24100851 | 0.81 | MAPT (0.43) | USP7MAPK14USP10USP47ALDH1A1 | |
| SCHEMBL24101222 | 0.80 | KMT2A (0.46) | ALDH1A1HSD17B10CYP1A2CYP2C9MAPT | |
| SCHEMBL25996931 | 0.76 | USP7 (0.39) | USP7MAPK14USP10USP47 | |
| SCHEMBL24100866 | 0.76 | L3MBTL1 (0.43) | ALDH1A1HSD17B10CYP1A2CYP2C9KDM4E | |
| SCHEMBL24101159 | 0.75 | ITGB2 (0.44) | USP7USP47ALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL24100741 | 0.68 | MEN1 (0.46) | USP7ALDH1A1HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL30452220 | 0.67 | ALDH1A1 (0.46) | USP7MAPK14USP10USP47ALDH1A1 | |
| SCHEMBL576377 | 0.67 | ALDH1A1 (0.46) | USP7MAPK14USP10USP47ALDH1A1 | |
| SCHEMBL24101228 | 0.67 | POLB (0.43) | ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL24101187 | 0.66 | L3MBTL1 (0.55) | HSD17B10CYP1A2CYP2C9MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233533-A1 | COMPOSITIONS, METHODS OF TREATING AND PREVENTING FUNGAL INFECTIONS, AND METHODS OF INHIBITING PRP8 INTEIN EXPRESSION | HEALTH RESEARCH, INC. (US) | 2023-07-27 | — | — | US | disclosed |
| US-20230233533-A1 | COMPOSITIONS, METHODS OF TREATING AND PREVENTING FUNGAL INFECTIONS, AND METHODS OF INHIBITING PRP8 INTEIN EXPRESSION | HEALTH RESEARCH, INC. (US) | 2023-07-27 | — | — | US | disclosed |
| WO-2021252068-A1 | COMPOSITIONS, METHODS OF TREATING AND PREVENTING FUNGAL INFECTIONS, AND METHODS OF INHIBITING PRP8 INTEIN EXPRESSION | HEALTH RESEARCH, INC. (US) | 2021-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233533-A1 | COMPOSITIONS, METHODS OF TREATING AND PREVENTING FUNGAL INFECTIONS, AND METHODS OF INHIBITING PRP8 INTEIN EXPRESSION | PRPF8, PRPF40A, PRPF19 | USP7 668/4885MAPK14 2697/4885USP10 1879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.