SCHEMBL2411686

SCHEMBL2411686

COCc1ccc(CCl)cc1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AGXT P21549 6/20 0.38
IDO1 P14902 4/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
PTGS2 P35354 1/20 0.37
TTR P02766 2/20 0.36
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
ACACB O00763 1/20 0.34
ERN1 O75460 1/20 0.34
APP P05067 3/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL795694 0.93 ERN1 (0.41) AGXTIDO1CA1CA2PTGS2
Ether SCHEMBL8429378 0.89 PTGS2 (0.36) AGXTIDO1CA1CA2PTGS2
SCHEMBL10735808 0.89 TTR (0.42) AGXTIDO1TTRAPP
SCHEMBL134443 0.86 IDO1 (0.46) AGXTIDO1PTGS2LMNATP53
Methyl Alcohol SCHEMBL28236652 0.80 IDO1 (0.42) AGXTIDO1PTGS2LMNATP53
SCHEMBL12650418 0.80 AGXT (0.35) AGXTIDO1CA1CA2TTR
SCHEMBL31273 0.79 IDO1 (0.58) AGXTIDO1LMNAAPPALDH1A1
SCHEMBL4217287 0.78 PTPN2 (0.38) APP
SCHEMBL8020885 0.78 ESR1 (0.48) AGXTIDO1CA2PTGS2LMNA
SCHEMBL9679767 0.78 TSHR (0.52) AGXTIDO1CA1CA2PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146112-A1 PHOTO-MELT-BULK POLYMERIZATION FOR RECYCLABLE POLYDIENE-DERIVATIVES PURDUE RESEARCH FOUNDATION (US) 2026-05-28 US disclosed
US-20250302842-A1 HETEROCYCLIC COMPOUNDS USEFUL FOR TREATMENT OF CANCERS Jubilant Epipad LLC 2025-10-02 US disclosed
EP-3630779-B1 ANTIBIOTIC RESISTANCE BREAKERS KING S COLLEGE LONDON (GB) 2025-09-03 EP disclosed
US-12357639-B2 Heterocyclic compounds as pad inhibitors Jubilant Epipad LLC (US) 2025-07-15 US disclosed
CN-115128898-B Photosensitive resin composition and application thereof 北京鼎材科技有限公司 2024-06-11 CN disclosed
US-20240156831-A1 HETEROCYCLIC COMPOUNDS AS PAD INHIBITORS Jubilant Epipad LLC 2024-05-16 US disclosed
EP-3684767-B1 HETEROCYCLIC COMPOUNDS AS PAD INHIBITORS Jubilant Epipad LLC (US) 2024-04-24 EP disclosed
US-11833156-B2 Heterocyclic compounds as pad inhibitors Jubilant Epipad LLC (US) 2023-12-05 US disclosed
US-11746116-B2 Antibiotic resistance breakers KING'S COLLEGE LONDON (GB) 2023-09-05 US disclosed
US-11746116-B2 Antibiotic resistance breakers KING'S COLLEGE LONDON (GB) 2023-09-05 US disclosed
CN-110869373-A Antibiotic resistance disruptors 伦敦皇家学院 2020-03-06 CN disclosed
WO-2019058393-A1 HETEROCYCLIC COMPOUNDS AS PAD INHIBITORS JUBILANT BIOSYS LIMITED (IN) 2019-03-28 WO disclosed
US-10227588-B2 3′end caps for RNAi agents for use in RNA interference NOVARTIS AG (CH) 2019-03-12 US disclosed
US-9988627-B2 Formats for organic compounds for use in RNA interference NOVARTIS AG (CH) 2018-06-05 US disclosed
US-8026370-B2 Peroxisome proliferator antagonist; hyperlipemia agents; arteriosclerosis; antiischemic agents MITSUBISHI TANABE PHARMA CORPORATION (JP) 2011-09-27 US disclosed
US-20080167307-A1 Carboxylic Acid Derivative Containing Thiazole Ring and Pharmaceutical Use Thereof MITSUBISHI PHAMA CORPORATION (JP) 2008-07-10 US disclosed
EP-1816128-A1 CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF Mitsubishi Pharma Corporation (JP) 2007-08-08 EP disclosed
EP-0420941-B1 PROCESS FOR PRODUCTION OF AROMATIC ALDOXIMES ALLIED SIGNAL INC (US) 1994-01-12 EP disclosed
EP-0420941-A1 PROCESS FOR PRODUCTION OF AROMATIC ALDOXIMES. ALLIED SIGNAL INC (US) 1991-04-10 EP disclosed
WO-1989012623-A1 PROCESS FOR PRODUCTION OF AROMATIC ALDOXIMES ALLIED-SIGNAL INC. (US) 1989-12-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080167307-A1 Carboxylic Acid Derivative Containing Thiazole Ring and Pharmaceutical Use Thereof PPARA, PPARD, PPARG AGXT 711/4885IDO1 4505/4885CA1 3375/4885
US-11833156-B2 Heterocyclic compounds as pad inhibitors PADI4, PADI2, PADI1 AGXT 673/4885IDO1 1631/4885CA1 1200/4885
US-20250302842-A1 HETEROCYCLIC COMPOUNDS USEFUL FOR TREATMENT OF CANCERS NES, VHL, ETV6 AGXT 4056/4885IDO1 3062/4885CA1 566/4885
US-10227588-B2 3′end caps for RNAi agents for use in RNA interference RNGTT, NSUN2, NSUN3 AGXT 3556/4885IDO1 4611/4885CA1 4629/4885
US-20240156831-A1 HETEROCYCLIC COMPOUNDS AS PAD INHIBITORS PADI4, PADI2, PADI1 AGXT 681/4885IDO1 872/4885CA1 2800/4885
US-11746116-B2 Antibiotic resistance breakers ABCC1, ARL1, AKR1C3 AGXT 302/4885IDO1 745/4885CA1 3072/4885
US-12357639-B2 Heterocyclic compounds as pad inhibitors PADI4, PADI2, PADI1 AGXT 681/4885IDO1 872/4885CA1 2800/4885
US-20260146112-A1 PHOTO-MELT-BULK POLYMERIZATION FOR RECYCLABLE POLYDIENE-DERIVATIVES MUC1, PARP1, PARP2 AGXT 4873/4885IDO1 3419/4885CA1 3855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.