Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.35 |
| ▸ | HTR6 | P50406 | 11/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.34 |
| ▸ | IDE | P14735 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412415 | 0.93 | PTGDR2 (0.34) | HTR6PTGDR2HTR2AHTR7DHODH | |
| SCHEMBL2412127 | 0.91 | MET (0.39) | NFE2L2HTR6PTGDR2HTR2A | |
| SCHEMBL2408070 | 0.90 | PPME1 (0.34) | HTR6PTGDR2 | |
| SCHEMBL2408861 | 0.90 | FPR1 (0.33) | IDE | |
| SCHEMBL2409871 | 0.88 | PTGDR2 (0.33) | HTR6PTGDR2IDEHTR2AHTR2C | |
| SCHEMBL2409033 | 0.85 | PTGDR2 (0.32) | PTGDR2 | |
| SCHEMBL2407582 | 0.85 | MET (0.38) | PTGDR2 | |
| SCHEMBL2412156 | 0.84 | DCTPP1 (0.32) | PTGDR2 | |
| SCHEMBL2415885 | 0.83 | ADAMTS4 (0.31) | PTGDR2DHODH | |
| SCHEMBL2412351 | 0.83 | MET (0.40) | NFE2L2HTR6PTGDR2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |