Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.33 |
| ▸ | PDE4A | P27815 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.32 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | CCKAR | P32238 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411930 | 0.91 | EPHX2 (0.33) | — | |
| SCHEMBL2409033 | 0.91 | PTGDR2 (0.32) | PTGDR2CCKARGRM4 | |
| SCHEMBL2415885 | 0.91 | ADAMTS4 (0.31) | PTGDR2CCKAR | |
| SCHEMBL2412351 | 0.90 | MET (0.40) | METPTGDR2MMP2MMP9MMP8 | |
| SCHEMBL2410113 | 0.89 | APLNR (0.35) | PTGDR2 | |
| SCHEMBL2411039 | 0.89 | ABCC9 (0.34) | MMP2MMP9MMP8MMP13CYP2C9 | |
| SCHEMBL2408487 | 0.88 | HDAC3 (0.31) | — | |
| SCHEMBL2409439 | 0.88 | MMP2 (0.33) | PTGDR2CCKARMMP2MMP9MMP8 | |
| SCHEMBL2194752 | 0.87 | MMP2 (0.33) | PTGDR2CCKARMMP2MMP9MMP8 | |
| SCHEMBL2192366 | 0.87 | DCTPP1 (0.31) | MMP2MMP9MMP8MMP13CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |