Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2413993 | 0.82 | HDAC6 (0.58) | ALDH1A1LMNASMN1; SMN2HTTTBXA2R | |
| SCHEMBL2410851 | 0.79 | CA1 (0.44) | ALDH1A1LMNASMN1; SMN2HTTTMPRSS6 | |
| SCHEMBL9660601 | 0.78 | TBXA2R (0.70) | ALDH1A1LMNASMN1; SMN2HTTTBXA2R | |
| SCHEMBL11887279 | 0.77 | CES2 (0.55) | ALDH1A1LMNACA1CA2MAPT | |
| SCHEMBL10447516 | 0.76 | TAAR1 (0.70) | ALDH1A1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL2412284 | 0.76 | CYP3A4 (0.53) | ALDH1A1LMNAHTTTMPRSS6F2 | |
| SCHEMBL2407249 | 0.76 | CYP3A4 (0.53) | ALDH1A1LMNAHTTTMPRSS6F2 | |
| SCHEMBL14280991 | 0.75 | MMP1 (0.62) | ALDH1A1LMNASMN1; SMN2TMPRSS6MEN1 | |
| SCHEMBL4894513 | 0.74 | HTT (0.48) | ALDH1A1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL5185902 | 0.74 | ALDH1A1 (0.56) | ALDH1A1LMNASMN1; SMN2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106632-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |