Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24144136 | 0.85 | CYP19A1 (0.44) | NR1D1SMN1; SMN2CNR2CNR1TBXA2R | |
| SCHEMBL24144536 | 0.79 | NR1D1 (0.71) | NR1D1 | |
| SCHEMBL30592469 | 0.79 | CAMK2D (0.46) | NR1D1SMN1; SMN2CNR2CNR1TBXA2R | |
| SCHEMBL26673710 | 0.79 | CAMK2D (0.46) | NR1D1SMN1; SMN2CNR2CNR1TBXA2R | |
| SCHEMBL24143488 | 0.79 | NR1D1 (0.44) | NR1D1SMN1; SMN2CNR2CNR1TBXA2R | |
| SCHEMBL24144934 | 0.77 | NR1D1 (0.42) | NR1D1SMN1; SMN2CNR2CNR1TBXA2R | |
| SCHEMBL24143978 | 0.71 | SMN1; SMN2 (0.36) | NR1D1SMN1; SMN2CNR2CNR1TBXAS1 | |
| SCHEMBL24143495 | 0.69 | NR1D1 (0.41) | NR1D1SMN1; SMN2CNR2CNR1GSK3B | |
| SCHEMBL22122330 | 0.69 | LMNA (0.45) | SMN1; SMN2CNR2CNR1TBXAS1HTR6 | |
| SCHEMBL24142955 | 0.68 | ICMT (0.44) | NR1D1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021263278-A1 | REV-ERB AGONISTS FOR THE TREATMENT OF TH17-MEDIATED INFLAMMATORY DISORDERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-12-30 | — | — | WO | disclosed |