Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24152849 | 0.91 | MGAT2 (0.49) | ALDH1A1PKMSYKMGAT2 | |
| SCHEMBL24151798 | 0.88 | SYK (0.44) | ALDH1A1KMT2ASYKMAPTMGAT2 | |
| SCHEMBL24152858 | 0.87 | NTRK1 (0.46) | KMT2ASYKMGAT2 | |
| SCHEMBL24152477 | 0.86 | SYK (0.49) | SMN1; SMN2ALDH1A1KMT2ASYKMAPT | |
| SCHEMBL24151507 | 0.85 | SYK (0.53) | ALDH1A1KMT2ASYKMAPT | |
| SCHEMBL24152577 | 0.83 | SCN3A (0.53) | SYKMGAT2 | |
| SCHEMBL24152348 | 0.83 | SYK (0.47) | SYKMGAT2 | |
| SCHEMBL24151529 | 0.83 | SYK (0.61) | SMN1; SMN2ALDH1A1SYK | |
| SCHEMBL24152421 | 0.82 | LMNA (0.44) | ALDH1A1SYKMAPT | |
| SCHEMBL24151530 | 0.82 | SYK (0.48) | SMN1; SMN2SYKGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |