Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.49 |
| ▸ | SRC | P12931 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24151798 | 0.91 | SYK (0.44) | SYKSRCMGAT2ALDH1A1MEN1 | |
| SCHEMBL24152849 | 0.91 | MGAT2 (0.49) | SYKSRCLMNAMGAT2ALDH1A1 | |
| SCHEMBL24151529 | 0.90 | SYK (0.61) | SYKSRCLMNASMN1; SMN2HTT | |
| SCHEMBL24152348 | 0.90 | SYK (0.47) | SYKSRCATMMGAT2KDM4E | |
| SCHEMBL24152577 | 0.89 | SCN3A (0.53) | SYKSRCMGAT2CDK2 | |
| SCHEMBL24151508 | 0.86 | IDO1 (0.47) | SYKSMN1; SMN2MGAT2ALDH1A1KMT2A | |
| SCHEMBL24151530 | 0.85 | SYK (0.48) | SYKSRCSMN1; SMN2HTT | |
| SCHEMBL24152858 | 0.85 | NTRK1 (0.46) | SYKSRCMGAT2MEN1KMT2A | |
| SCHEMBL24151507 | 0.85 | SYK (0.53) | SYKLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL24152351 | 0.82 | NTRK1 (0.45) | SYKSRCMGAT2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |