Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAT2 | Q10469 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 3/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.39 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | FCER2 | P06734 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24151508 | 0.91 | IDO1 (0.47) | MGAT2SYKPKMALDH1A1 | |
| SCHEMBL24151798 | 0.91 | SYK (0.44) | MGAT2SYKSRCPDPK1POLB | |
| SCHEMBL24152477 | 0.91 | SYK (0.49) | MGAT2SYKSRCLMNAPOLB | |
| SCHEMBL24152858 | 0.90 | NTRK1 (0.46) | MGAT2SYKNTRK1SRC | |
| SCHEMBL24152577 | 0.88 | SCN3A (0.53) | MGAT2SYKNTRK1SRCCDK2 | |
| SCHEMBL24151529 | 0.88 | SYK (0.61) | SYKNTRK1SRCLMNAFCER2 | |
| SCHEMBL24152348 | 0.88 | SYK (0.47) | MGAT2SYKSRCPOLBCDK2 | |
| SCHEMBL24151507 | 0.88 | SYK (0.53) | SYKNTRK1LMNAPOLBFCER2 | |
| SCHEMBL24152421 | 0.87 | LMNA (0.44) | SYKSRCLMNAPOLBMAPK1 | |
| SCHEMBL24151530 | 0.85 | SYK (0.48) | SYKNTRK1SRCFCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |