Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.47 |
| ▸ | SRC | P12931 | 5/20 | 0.43 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | GLB1 | P16278 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | FCER2 | P06734 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24152477 | 0.90 | SYK (0.49) | SYKSRCMGAT2POLBCDK2 | |
| SCHEMBL24152849 | 0.88 | MGAT2 (0.49) | SYKSRCMGAT2POLBCDK2 | |
| SCHEMBL24151529 | 0.88 | SYK (0.61) | SYKSRCFCER2 | |
| SCHEMBL24152577 | 0.86 | SCN3A (0.53) | SYKSRCMGAT2CDK2SCN3A | |
| SCHEMBL24151798 | 0.85 | SYK (0.44) | SYKSRCMGAT2POLBCDK2 | |
| SCHEMBL24151508 | 0.83 | IDO1 (0.47) | SYKMGAT2 | |
| SCHEMBL24151530 | 0.83 | SYK (0.48) | SYKSRCFCER2 | |
| SCHEMBL24152858 | 0.83 | NTRK1 (0.46) | SYKSRCMGAT2 | |
| SCHEMBL24151507 | 0.82 | SYK (0.53) | SYKPOLBFCER2 | |
| SCHEMBL24152421 | 0.82 | LMNA (0.44) | SYKSRCPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |