Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24152365 | 0.83 | TRPA1 (0.34) | SCN9A | |
| SCHEMBL24153262 | 0.79 | TRPA1 (0.36) | — | |
| SCHEMBL24152352 | 0.77 | MAOA (0.41) | SCN9A | |
| SCHEMBL24153260 | 0.77 | TRPA1 (0.36) | SCN9A | |
| SCHEMBL24152457 | 0.75 | KDM4E (0.33) | — | |
| SCHEMBL24152458 | 0.75 | TRPA1 (0.35) | SCN9A | |
| SCHEMBL24152507 | 0.75 | KDM4E (0.33) | SCN9A | |
| SCHEMBL24151584 | 0.74 | TRPA1 (0.42) | — | |
| SCHEMBL24153263 | 0.74 | TRPA1 (0.38) | — | |
| SCHEMBL24152367 | 0.74 | TRPA1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |