Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24153263 | 0.93 | TRPA1 (0.38) | TRPA1CA1CA2POLBMAPT | |
| SCHEMBL24151584 | 0.92 | TRPA1 (0.42) | TRPA1POLBMAPTSTAT3SMN1; SMN2 | |
| SCHEMBL24153260 | 0.91 | TRPA1 (0.36) | TRPA1MAOACA1CA2POLB | |
| SCHEMBL24152367 | 0.84 | TRPA1 (0.41) | TRPA1POLBMAPTSTAT3SMN1; SMN2 | |
| SCHEMBL24153249 | 0.84 | TRPA1 (0.41) | TRPA1PTGS1PTGS2MAOACA1 | |
| SCHEMBL24152365 | 0.83 | TRPA1 (0.34) | TRPA1PTGS1PTGS2MAOACA1 | |
| SCHEMBL24152463 | 0.82 | TRPA1 (0.41) | TRPA1POLBMAPTSTAT3SMN1; SMN2 | |
| SCHEMBL24152375 | 0.82 | TRPA1 (0.41) | TRPA1MAPTSMN1; SMN2PRNP | |
| SCHEMBL24152377 | 0.81 | TRPA1 (0.48) | TRPA1MAOAPOLBMAPTSMN1; SMN2 | |
| SCHEMBL24151587 | 0.81 | TRPA1 (0.42) | TRPA1POLBMAPTSTAT3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |