Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24152366 | 0.83 | RORC (0.32) | SCN9A | |
| SCHEMBL24153262 | 0.83 | TRPA1 (0.36) | TRPA1CA1CA2PTGS1PTGS2 | |
| SCHEMBL24152352 | 0.82 | MAOA (0.41) | TRPA1BRD4CA1CA2PTGS1 | |
| SCHEMBL24152458 | 0.81 | TRPA1 (0.35) | TRPA1BRD4CA1CA2PTGS1 | |
| SCHEMBL24153260 | 0.81 | TRPA1 (0.36) | TRPA1CA1CA2MAOAMAOB | |
| SCHEMBL24151584 | 0.79 | TRPA1 (0.42) | TRPA1CASP3SCN1ASCN1BSCN5A | |
| SCHEMBL24152819 | 0.79 | RXFP1 (0.34) | TRPA1BRD4CA1CA2PTGS1 | |
| SCHEMBL24152504 | 0.78 | TAS2R14 (0.41) | TRPA1PTGS1PTGS2MAOAMAOB | |
| SCHEMBL24152367 | 0.78 | TRPA1 (0.41) | TRPA1CASP3SCN1ASCN1BSCN5A | |
| SCHEMBL24153263 | 0.78 | TRPA1 (0.38) | TRPA1BRD4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |