Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 6/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.32 |
| ▸ | SCN1A | P35498 | 2/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24151584 | 0.91 | TRPA1 (0.42) | TRPA1CASP3SCN5ASCN1ASCN8A | |
| SCHEMBL24153262 | 0.91 | TRPA1 (0.36) | TRPA1MAOAMAOBCASP3MAPT | |
| SCHEMBL24153263 | 0.87 | TRPA1 (0.38) | TRPA1MAPTPOLBSTAT3SMN1; SMN2 | |
| SCHEMBL24152367 | 0.85 | TRPA1 (0.41) | TRPA1CASP3SCN5ASCN1ASCN8A | |
| SCHEMBL24152463 | 0.82 | TRPA1 (0.41) | TRPA1CASP3SCN5ASCN1ASCN8A | |
| SCHEMBL24152375 | 0.81 | TRPA1 (0.41) | TRPA1SCN5ASCN1ASCN8AMAPT | |
| SCHEMBL24152365 | 0.81 | TRPA1 (0.34) | TRPA1MAOAMAOBCASP3SCN5A | |
| SCHEMBL24152377 | 0.81 | TRPA1 (0.48) | TRPA1MAOAMAOBCASP3SCN5A | |
| SCHEMBL24151587 | 0.81 | TRPA1 (0.42) | TRPA1CASP3SCN5ASCN1ASCN8A | |
| SCHEMBL24151575 | 0.79 | TRPA1 (0.61) | TRPA1CASP3MAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |