SCHEMBL24154705

SCHEMBL24154705

CC(C)(C)OC(=O)N1CC2CCC1C=C2c1ccc(Cl)nc1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 2/20 0.38
GPR119 Q8TDV5 5/20 0.37
RET P07949 3/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA7 P36544 1/20 0.37
CHRNA4 P43681 1/20 0.37
HPGDS O60760 3/20 0.37
PIK3CD O00329 1/20 0.36
KCNK3 O14649 2/20 0.36
KCNK9 Q9NPC2 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30116755 1.00 USP30 (0.38) USP30GPR119RETCHRNB2CHRNB4
SCHEMBL31571866 0.82 HPGDS (0.36) GPR119HPGDSKCNK3KCNK9
SCHEMBL2494858 0.81 RET (0.37) USP30GPR119RETCHRNB2CHRNB4
SCHEMBL30382486 0.81 GPR119 (0.47) USP30GPR119HPGDS
SCHEMBL24154706 0.81 GPR119 (0.47) USP30GPR119HPGDS
SCHEMBL24155175 0.76 CHRNB2 (0.44) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL30116749 0.76 CHRNB2 (0.44) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL5939918 0.74 USP30 (0.41) USP30GPR119RETCHRNB2CHRNB4
SCHEMBL5939915 0.74 USP30 (0.41) USP30GPR119RETCHRNB2CHRNB4
SCHEMBL31164477 0.72 GRM2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225323-A1 COMPOSITIONS AND METHODS FOR PARASITE CONTROL PHILIP MORRIS PRODUCTS S.A. (CH) 2023-07-20 US disclosed
US-20230225323-A1 COMPOSITIONS AND METHODS FOR PARASITE CONTROL PHILIP MORRIS PRODUCTS S.A. (CH) 2023-07-20 US disclosed
US-20230225323-A1 COMPOSITIONS AND METHODS FOR PARASITE CONTROL PHILIP MORRIS PRODUCTS S.A. (CH) 2023-07-20 US disclosed
EP-4172156-A1 COMPOSITIONS AND METHODS FOR PARASITE CONTROL Philip Morris Products S.A. (CH) 2023-05-03 EP disclosed
CN-115698002-A Compositions and methods for parasite control 菲利普莫里斯生产公司 2023-02-03 CN disclosed
WO-2021260029-A1 COMPOSITIONS AND METHODS FOR PARASITE CONTROL PHILIP MORRIS PRODUCTS S.A. (CH) 2021-12-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225323-A1 COMPOSITIONS AND METHODS FOR PARASITE CONTROL TRHDE, CUTA, PIGS USP30 2170/4885GPR119 4418/4885RET 2688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.