SCHEMBL24196868

SCHEMBL24196868

CN(N)CC1CCN(CCN)CC1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.45
CARM1 Q86X55 1/20 0.45
PRMT6 Q96LA8 1/20 0.45
PRMT1 Q99873 1/20 0.45
PRMT8 Q9NR22 1/20 0.45
ALOX15 P16050 1/20 0.44
GNAI3 P08754 3/20 0.43
GNAO1 P09471 3/20 0.43
GNAI1 P63096 3/20 0.43
NCF1 P14598 1/20 0.38
ABL1 P00519 1/20 0.30
FYN P06241 1/20 0.30
YES1 P07947 1/20 0.30
FGR P09769 1/20 0.30
SRC P12931 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9824832 0.79 GNAO1 (0.45) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL1628330 0.75 ALOX15 (0.52) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL13569909 0.74 NCF1 (0.58) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL5178698 0.74 PRMT3 (0.42) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL1306996 0.74 ALOX15 (0.50) PRMT3CARM1PRMT6PRMT1PRMT8
Hydrochloric Acid SCHEMBL598320 0.74 GNAO1 (0.54) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL19724719 0.73
SCHEMBL9824415 0.73 SIGMAR1 (0.44) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL11410375 0.73 ALOX15 (0.55) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL24207822 0.72 GNAO1 (0.53) PRMT3CARM1PRMT6PRMT1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022008475-A1 INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER UNIVERSITE CLAUDE BERNARD LYON 1 (FR) 2022-01-13 WO disclosed