Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5177566 | 0.90 | KEAP1 (0.39) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL5178776 | 0.88 | CHRM1 (0.36) | GNAI3GNAO1GNAI1CHRM3 | |
| SCHEMBL9824832 | 0.80 | GNAO1 (0.45) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL5179307 | 0.78 | ALOX15 (0.42) | ALOX15GNAO1 | |
| SCHEMBL598481 | 0.77 | ALOX15 (0.48) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL5178556 | 0.77 | ALOX15 (0.38) | ALOX15GNAI3GNAO1GNAI1 | |
| SCHEMBL5180446 | 0.77 | CHRM1 (0.35) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL6783180 | 0.77 | ALOX15 (0.52) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL5179281 | 0.76 | ALOX15 (0.43) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL5177788 | 0.76 | NCF1 (0.41) | PRMT3CARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927174-B1 | NEW AMINO ALCOHOL DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND MEDICAMENTS AND REAGENTS CONTAINING THESE COMPOUNDS | MEDIGENE AG (DE) | 2007-12-12 | — | — | EP | disclosed |
| US-7097854-B2 | Amino alcohol derivatives, process for their production and pharmaceutical preparations and reagents containing these compounds | MEDIGENE ONCOLOGY GMBH (DE) | 2006-08-29 | — | — | US | disclosed |
| US-20030236266-A1 | Amino alcohol derivatives, process for their production and pharmaceutical preparations and reagents containing these compounds | ROCHE DIAGNOSTICS GMBH | 2003-12-25 | — | — | US | disclosed |
| CN-1087293-C | New amino alcohol derivatives, process for production thereof and medicaments and reagents containing these compounds | ROHER DIAGNOSTIC EQUIPMENT AG (DE) | 2002-07-10 | — | — | CN | disclosed |
| CN-1237161-A | New amino alcohol derivatives, process for production thereof and medicaments and reagents containing these compounds | ROHER DIAGNOSTIC EQUIPMENT AG (DE) | 1999-12-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236266-A1 | Amino alcohol derivatives, process for their production and pharmaceutical preparations and reagents containing these compounds | ADH1C, ADH1A, ADH5 | PRMT3 83/4885CARM1 96/4885PRMT6 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.