Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24196867 | 0.81 | CTDSP1 (0.37) | ALDH1A1KDM4EPOLBKMT2ALMNA | |
| SCHEMBL24904186 | 0.76 | HDAC3 (0.42) | ALDH1A1POLBKMT2ALMNAFFAR4 | |
| SCHEMBL24196886 | 0.75 | MAPT (0.35) | ALDH1A1KMT2ALMNANPSR1MAPT | |
| SCHEMBL24196890 | 0.75 | PTPN1 (0.37) | ALDH1A1ACACBMAPTACACASMN1; SMN2 | |
| SCHEMBL24196887 | 0.74 | CA2 (0.34) | ALDH1A1POLBKMT2ALMNAGAA | |
| SCHEMBL24196865 | 0.73 | SIGMAR1 (0.36) | KMT2ALMNAGAAMAPT | |
| SCHEMBL24196877 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KMT2APARP10LMNAACACB | |
| SCHEMBL2786249 | 0.73 | ALDH1A3 (0.47) | ALDH1A1ALDH1A3POLBKMT2AGLA | |
| SCHEMBL22572707 | 0.72 | HDAC3 (0.44) | ALDH1A1KMT2ALMNAGAAMAPT | |
| SCHEMBL24732442 | 0.72 | MAPT (0.50) | ALDH1A1KDM4EALDH1A3POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022008475-A1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2022-01-13 | — | — | WO | disclosed |