Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24200130 | 0.88 | TBXAS1 (0.39) | KDM4EALDH1A1MAPTL3MBTL1HPGD | |
| SCHEMBL24199930 | 0.80 | CFD (0.35) | KDM4EALDH1A1MAPTL3MBTL1HPGD | |
| SCHEMBL24200119 | 0.78 | MEN1 (0.33) | ALDH1A1MAPTL3MBTL1HPGDTDP1 | |
| SCHEMBL25913045 | 0.75 | L3MBTL1 (0.49) | KDM4EALDH1A1MAPTL3MBTL1HPGD | |
| SCHEMBL21438503 | 0.75 | RECQL (0.46) | KDM4EALDH1A1MAPTL3MBTL1HPGD | |
| SCHEMBL21455980 | 0.73 | ALDH1A1 (0.36) | ALDH1A1MAPTL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL24200170 | 0.73 | TBXAS1 (0.42) | ALDH1A1MAPTL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL6862344 | 0.72 | L3MBTL1 (0.49) | KDM4EALDH1A1MAPTL3MBTL1HPGD | |
| SCHEMBL11836751 | 0.72 | L3MBTL1 (0.43) | KDM4EALDH1A1MAPTL3MBTL1HPGD | |
| SCHEMBL21455422 | 0.71 | KMT2A (0.34) | KDM4EALDH1A1MAPTL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |