Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21455436 | 0.80 | MEN1 (0.37) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL24199970 | 0.79 | PTGS2 (0.34) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL24200227 | 0.79 | MEN1 (0.34) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL24200130 | 0.79 | TBXAS1 (0.39) | MEN1KMT2ANPSR1HPGDALDH1A1 | |
| SCHEMBL24200319 | 0.79 | MEN1 (0.32) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL21455802 | 0.79 | ALDH1A1 (0.42) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL24199932 | 0.78 | KDM4E (0.36) | MEN1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL24200210 | 0.78 | MEN1 (0.33) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL23617338 | 0.78 | MEN1 (0.39) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL21455828 | 0.77 | MEN1 (0.32) | MEN1KMT2ANPSR1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |