Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 3/20 | 0.35 |
| ▸ | F11 | P03951 | 2/20 | 0.33 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24199932 | 0.80 | KDM4E (0.36) | L3MBTL1DHODHHPGDALDH1A1MAPT | |
| SCHEMBL24200155 | 0.76 | MRGPRX4 (0.35) | CFDL3MBTL1MRGPRX4DHODHALDH1A1 | |
| SCHEMBL24199931 | 0.73 | CFD (0.42) | CFDF11TPSB2PLAUPLG | |
| SCHEMBL24200224 | 0.71 | TBXAS1 (0.35) | CFDPTGS2L3MBTL1MRGPRX4DHODH | |
| SCHEMBL21455759 | 0.71 | L3MBTL1 (0.40) | CFDPTGS2L3MBTL1MRGPRX4HPGD | |
| SCHEMBL24200130 | 0.70 | TBXAS1 (0.39) | L3MBTL1HPGDALDH1A1MAPTGAA | |
| SCHEMBL23617310 | 0.69 | L3MBTL1 (0.40) | CFDPTGS2L3MBTL1MRGPRX4HPGD | |
| SCHEMBL21438503 | 0.68 | RECQL (0.46) | L3MBTL1HPGDALDH1A1MAPTGAA | |
| SCHEMBL25913045 | 0.68 | L3MBTL1 (0.49) | L3MBTL1HPGDALDH1A1MAPTRAB9A | |
| SCHEMBL21455293 | 0.67 | DPP4 (0.35) | CFDL3MBTL1MRGPRX4HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |