SCHEMBL2420083

SCHEMBL2420083

Oc1ccccc1O[SiH2]c1ccccc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.46
TP53 P04637 2/20 0.46
TSHR P16473 2/20 0.46
CA1 P00915 1/20 0.46
GAA P10253 4/20 0.43
LMNA P02545 3/20 0.43
MAPT P10636 3/20 0.43
JAK2 O60674 1/20 0.43
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 3/20 0.38
HPGD P15428 3/20 0.38
HSD17B10 Q99714 3/20 0.38
ALOX15 P16050 3/20 0.38
CYP3A4 P08684 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
POLB P06746 2/20 0.38
NPC1 O15118 1/20 0.38
CA12 O43570 1/20 0.38
GMNN O75496 1/20 0.38
EGFR P00533 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL9162098 0.92 GAA (0.41) CA2TP53TSHRCA1GAA
Phenol SCHEMBL6858850 0.92 CA2 (0.41) CA2TP53TSHRCA1GAA
SCHEMBL4636948 0.85 CA2 (0.35) CA2TP53TSHRCA1GAA
SCHEMBL28459068 0.84 CA1 (0.55) CA2TP53TSHRCA1LMNA
4-Vinylphenol SCHEMBL4451040 0.82 TRPA1 (0.37) CA2TP53TSHRCA1GAA
2-Allylphenol SCHEMBL4453155 0.81 GABRA1 (0.38) TSHRGAALMNAMAPTJAK2
Chavicol SCHEMBL4444837 0.79 ALDH1A1 (0.41) CA2TP53TSHRCA1GAA
SCHEMBL4449489 0.77 GAA (0.39) CA2TSHRCA1GAALMNA
SCHEMBL9775497 0.77 LMNA (0.45) CA2TP53TSHRCA1GAA
SCHEMBL170029 0.73 LMNA (0.41) CA2TP53TSHRCA1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112824450-A Low-temperature-resistant high-fluidity flame-retardant PC 广东新通彩材料科技有限公司 2021-05-21 CN claimed
EP-2691461-B1 ELECTRICAL TRACKING RESISTANCE COMPOSITIONS, METHODS&ARTICLES OF MANUFACTURE SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-11-22 EP claimed
EP-2691460-B1 ELECTRICAL TRACKING RESISTANCE COMPOSITIONS, METHODS&ARTICLES OF MANUFACTURE SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-08-02 EP claimed
EP-2691473-B1 FLAME RETARDANT POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2015-04-22 EP claimed
EP-1530606-B1 SILOXANE BISCHLOROFORMATES SABIC INNOVATIVE PLASTICS IP (NL) 2010-12-08 EP claimed
EP-1937693-A1 SILOXANE BISCHLOROFORMATES General Electric Company (US) 2008-07-02 EP claimed
CN-1324071-C Siloxane bischloroformates GEN ELECTRIC (US) 2007-07-04 CN claimed
US-20070093629-A1 Siloxane bishchloroformates GENERAL ELECTRIC COMPANY (US) 2007-04-26 US claimed
WO-2007037888-A1 SILOXANE BISCHLOROFORMATES GENERAL ELECTRIC COMPANY (US) 2007-04-05 WO claimed
CN-1688634-A Siloxane bischloroformates GEN ELECTRIC (US) 2005-10-26 CN claimed
EP-1530606-A1 SILOXANE BISCHLOROFORMATES GENERAL ELECTRIC COMPANY (US) 2005-05-18 EP claimed
US-20040133024-A1 Siloxane bischloroformates SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2004-07-08 US claimed
US-6723864-B2 CONTINUOUS PROCESS BY PHOSGENATING SILOXANE BISPHENOLS IN A FLOW REACTOR USING A SUBSTANTIAL EXCESS OF PHOSGENE AND SODIUM HYDROXIDE GENERAL ELECTRIC COMPANY 2004-04-20 US claimed
WO-2004016675-A1 SILOXANE BISCHLOROFORMATES GENERAL ELECTRIC COMPANY (US) 2004-02-26 WO claimed
US-20040039218-A1 A continuous process by phosgenating siloxane bisphenols in a flow reactor using a substantial excess of phosgene and sodium hydroxide to achieve high yields and very pure product; intermediates for polycarbonatesiloxanes GENERAL ELECTRIC COMPANY 2004-02-26 US claimed
US-4478981-A CONTACT LENSES PETRARCH SYSTEMS INC. (US) 1984-10-23 US claimed
EP-4288482-B1 LINEAR BLOCK COPOLYMER TOUGHENER WITH ACRYLATE FUNCTIONAL GROUPS ELE CORP (US) 2025-07-30 EP disclosed
US-12122881-B2 Linear block copolymer toughener with acrylate functional groups ELE' CORPORATION (US) 2024-10-22 US disclosed
EP-0298279-A2 Electrostatographic toner and developer compositions EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-01-11 EP disclosed
US-4758491-A Dry toner and developer composition EASTMAN KODAK COMPANY (US) 1988-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040133024-A1 Siloxane bischloroformates PSMA2, PSMA3, PSMA4 CA2 1199/4885TP53 902/4885TSHR 4080/4885
US-20040039218-A1 A continuous process by phosgenating siloxane bisphenols in a flow reactor using a substantial excess of phosgene and sodium hydroxide to achieve high yields and very pure product; intermediates for polycarbonatesiloxanes PSPH, PAH, SEM1 CA2 626/4885TP53 1259/4885TSHR 4127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.