SCHEMBL24201117

SCHEMBL24201117

CCN1Cc2cccc(n2)CN(CC(=O)O)CCN(CC(=O)O)CC1C

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 13/20 0.40
SIGMAR1 Q99720 1/20 0.39
ALDH1A1 P00352 1/20 0.38
CYP2D6 P10635 1/20 0.38
CHRM1 P11229 1/20 0.37
DRD2 P14416 1/20 0.36
DRD4 P21917 1/20 0.36
OGA O60502 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16021612 0.93 SLC6A9 (0.44) SLC6A9
SCHEMBL9205301 0.82 EGLN1 (0.40) SLC6A9ALDH1A1
SCHEMBL19389460 0.81 SLC6A9 (0.37) SLC6A9ALDH1A1DRD2DRD4
SCHEMBL23975536 0.81 SLC6A9 (0.36) SLC6A9
SCHEMBL1394889 0.80 SLC6A9 (0.42) SLC6A9ALDH1A1
SCHEMBL10060134 0.80 CHIT1 (0.37) SLC6A9ALDH1A1DRD2DRD4
SCHEMBL19519825 0.80 SLC6A9 (0.37) SLC6A9DRD2DRD4
SCHEMBL9024977 0.80 SIGMAR1 (0.35) SLC6A9SIGMAR1DRD2DRD4
SCHEMBL30764646 0.78 NPC1 (0.35) SLC6A9CHRM1DRD2DRD4
SCHEMBL12544369 0.78 CYP2C19 (0.43) ALDH1A1CYP2D6CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3939972-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS Molecular Insight Pharmaceuticals, Inc. (US) 2022-01-19 EP disclosed