Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16021612 | 0.84 | SLC6A9 (0.44) | SLC6A9 | |
| SCHEMBL9266166 | 0.84 | SLC6A9 (0.34) | SLC6A9POLB | |
| SCHEMBL18807567 | 0.83 | FOLH1 (0.34) | SIGMAR1 | |
| SCHEMBL18807569 | 0.83 | L3MBTL1 (0.38) | SLC6A9POLBDRD2DRD4 | |
| SCHEMBL10060134 | 0.83 | CHIT1 (0.37) | SLC6A9DRD2DRD4 | |
| SCHEMBL9906195 | 0.83 | CHIT1 (0.37) | SIGMAR1 | |
| SCHEMBL16644695 | 0.83 | CHIT1 (0.37) | SIGMAR1 | |
| SCHEMBL19389406 | 0.83 | L3MBTL1 (0.38) | SLC6A9POLBDRD2DRD4 | |
| SCHEMBL9205301 | 0.83 | EGLN1 (0.40) | SLC6A9POLB | |
| SCHEMBL9024007 | 0.82 | NR1D1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438206-B1 | 6-Ring-containing macrocyclic tetraaza compounds, processes for their preparation, and pharmaceutical agents containing them | SCHERING AG (DE) | 1996-08-21 | — | — | EP | disclosed |
| US-5403572-A | Macrocyclic polyaza compounds containing 5 or 6 membered rings, process for producing them and pharmaceutical media containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-04-04 | — | — | US | disclosed |
| US-5334371-A | Marcocyclic polyaza bicyclo compounds containing 5 or 6 membered rings, and method for MRI | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-08-02 | — | — | US | disclosed |
| EP-0438206-A1 | 6-Ring-containing macrocyclic tetraaza compounds, processes for their preparation, and pharmaceutical agents containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-07-24 | — | — | EP | disclosed |