Sugi Predict

Sugi Predict / Compounds / SCHEMBL2421456

SCHEMBL2421456

SCHEMBL2421456

Cc1cc(O)c(N)cc1Cl

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CD44 P16070 1/20 0.65
▸ LMNA P02545 2/20 0.52
▸ ALDH1A1 P00352 8/20 0.47
▸ CYP3A4 P08684 5/20 0.47
▸ GAA P10253 5/20 0.47
▸ MAPT P10636 4/20 0.47
▸ ALOX15 P16050 4/20 0.43
▸ KDM4E B2RXH2 4/20 0.43
▸ HSD17B10 Q99714 3/20 0.43
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ HPGD P15428 2/20 0.43
▸ ALOX12 P18054 2/20 0.43
▸ MAPK1 P28482 2/20 0.43
▸ CA1 P00915 2/20 0.38
▸ CA2 P00918 2/20 0.38
▸ TSHR P16473 1/20 0.38
▸ CASP1 P29466 1/20 0.38
▸ PDE10A Q9Y233 1/20 0.38
▸ CA12 O43570 1/20 0.38
▸ CA7 P43166 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27937326 0.98 CD44 (0.62) CD44LMNAALDH1A1CYP3A4GAA
SCHEMBL4544583 0.91 CD44 (0.65) CD44LMNAALDH1A1CYP3A4GAA
SCHEMBL10827856 0.81 CD44 (0.52) CD44LMNAALDH1A1CYP3A4GAA
SCHEMBL404439 0.79 CD44 (1.00) CD44LMNAALDH1A1CYP3A4GAA
SCHEMBL2662863 0.79 LMNA (0.60) CD44LMNAALDH1A1CYP3A4GAA
SCHEMBL4750720 0.79 HSD17B10 (0.56) CD44ALDH1A1CYP3A4GAAMAPT
SCHEMBL2955553 0.79 CYP3A4 (0.55) CD44LMNAALDH1A1CYP3A4GAA
SCHEMBL29739478 0.77 CD44 (0.75) CD44LMNAALDH1A1CYP3A4GAA
SCHEMBL8341703 0.77 CD44 (0.75) CD44LMNAALDH1A1CYP3A4GAA
Hydrochloric Acid SCHEMBL7676240 0.77 CD44 (0.94) CD44LMNAALDH1A1CYP3A4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12459906-B2 3-(5-chloro-2-oxobenzo[d]oxazol-3(2H)-yl) propanoic acid derivatives as KMO inhibitors DR. FALK PHARMA GMBH (DE) 2025-11-04 — — US disclosed
EP-4623914-A1 USE OF 8-HYDROXYQUINOLINE DERIVATIVE Jiangsu Yahong Meditech Co., Ltd. (CN) 2025-10-01 — — EP disclosed
CN-120035438-A Use of 8-hydroxyquinoline derivatives 江苏亚虹医药科技股份有限公司 2025-05-23 — — CN disclosed
US-20240246916-A1 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVES, PREPARATION METHOD THEREFORE AND MEDICAL USE THEREOF JIANGSU YAHONG MEDITECH CO., LTD. (CN) 2024-07-25 — — US disclosed
WO-2024109684-A1 USE OF 8-HYDROXYQUINOLINE DERIVATIVE 江苏亚虹医药科技股份有限公司 2024-05-30 — — WO disclosed
CN-118059101-A Use of 8-hydroxyquinoline derivatives 江苏亚虹医药科技股份有限公司 2024-05-24 — — CN disclosed
EP-4349815-A1 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF Jiangsu Yahong Meditech Co., Ltd. (CN) 2024-04-10 — — EP disclosed
CN-117043141-A 7-nitro-8-hydroxyquinoline derivative, preparation method and medical application thereof 江苏亚虹医药科技股份有限公司 2023-11-10 — — CN disclosed
WO-2022253152-A1 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF 江苏亚虹医药科技股份有限公司 2022-12-08 — — WO disclosed
WO-2022253152-A1 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF 江苏亚虹医药科技股份有限公司 2022-12-08 — — WO disclosed
EP-0579204-A2 Dye composition for a keratinous fiber KAO CORPORATION (JP) 1994-01-19 — — EP disclosed
US-4859568-A Photographic image recording method using silver halide and vinyl monomer FUJI PHOTO FILM CO., LTD. (JP) 1989-08-22 — — US disclosed
US-4757135-A Copper-containing fiber reactive dye HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-12 — — US disclosed
EP-0183054-B1 COPPER FORMAZANE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1988-04-13 — — EP disclosed
EP-0183054-A1 Copper formazane compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1986-06-04 — — EP disclosed
US-4454225-A COUPLERS PREVENTING YELLOW IDSCOLORATION AT UNEXPOSED AREAS FUJI PHOTO FILM CO., LTD. (JP) 1984-06-12 — — US disclosed
US-4334011-A CYAN DYE FORMING COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1982-06-08 — — US disclosed
US-4207318-A ANTIALLERGIC ACTIVITY, BRONCHODILATOR ROUSSEL UCLAF (FR) 1980-06-10 — — US disclosed
US-4110246-A OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DE) 1978-08-29 — — US disclosed
US-4096157-A PIGMENTS HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240246916-A1 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVES, PREPARATION METHOD THEREFORE AND MEDICAL USE THEREOF CYP3A7, UGT1A7, UGT2B7 CD44 4300/4885LMNA 2723/4885ALDH1A1 1017/4885
US-12459906-B2 3-(5-chloro-2-oxobenzo[d]oxazol-3(2H)-yl) propanoic acid derivatives as KMO inhibitors KMO, AMY1A, AMY2A CD44 4763/4885LMNA 4076/4885ALDH1A1 1994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.