Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.46 |
| ▸ | ITGAL | P20701 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 2/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787235 | 0.78 | LMNA (0.61) | ABCG2ITGB2ICAM1ITGALLMNA | |
| SCHEMBL439199 | 0.77 | ABCG2 (0.52) | ABCG2ITGB2ICAM1ITGALLMNA | |
| SCHEMBL6269163 | 0.73 | LMNA (0.66) | ABCG2ITGB2ICAM1ITGALLMNA | |
| SCHEMBL13950599 | 0.73 | THRB (0.35) | LMNASMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL1038843 | 0.71 | ABCG2 (0.46) | ABCG2ITGB2ICAM1ITGALLMNA | |
| SCHEMBL442811 | 0.71 | ABCG2 (0.46) | ABCG2ITGB2ICAM1ITGALLMNA | |
| SCHEMBL438269 | 0.71 | ABCG2 (0.46) | ABCG2ITGB2ICAM1ITGALLMNA | |
| SCHEMBL279547 | 0.71 | ABCG2 (0.46) | ABCG2ITGB2ICAM1ITGALLMNA | |
| SCHEMBL29966720 | 0.71 | ABCG2 (0.46) | ABCG2ITGB2ICAM1ITGALLMNA | |
| SCHEMBL10195930 | 0.71 | MAOA (0.65) | ABCG2ITGB2ICAM1ITGALLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1540329-A4 | DRUG DISCOVERY METHOD | KEDDEM BIO SCIENCE LTD (IL) | 2009-06-10 | — | — | EP | claimed |
| JP-2006507480-A | — | — | 2006-03-02 | — | — | JP | claimed |
| EP-1540329-A1 | DRUG DISCOVERY METHOD | KEDDEM BIO-SCIENCE LTD. (IL) | 2005-06-15 | — | — | EP | claimed |
| WO-2004010136-A1 | DRUG DISCOVERY METHOD | KEDDEM BIO-SCIENCE LTD. (IL) | 2004-01-29 | — | — | WO | claimed |
| US-11697695-B2 | Polymerizable composition and optically anisotropic body using same | DIC CORPORATION (JP) | 2023-07-11 | — | — | US | disclosed |
| US-11697695-B2 | Polymerizable composition and optically anisotropic body using same | DIC CORPORATION (JP) | 2023-07-11 | — | — | US | disclosed |
| US-11186669-B2 | Polymerizable composition and optically anisotropic body using same | DIC CORPORATION (JP) | 2021-11-30 | — | — | US | disclosed |
| US-10927263-B2 | Polymerizable composition and optically anisotropic body produced using the same | DIC CORPORATION (JP) | 2021-02-23 | — | — | US | disclosed |
| US-10723952-B2 | Polymerizable compound and optically anisotropic body | DIC CORPORATION (JP) | 2020-07-28 | — | — | US | disclosed |
| US-20190264034-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY PRODUCED USING THE SAME | DIC CORPORATION (JP) | 2019-08-29 | — | — | US | disclosed |
| US-20190233565-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME | DIC CORPORATION (JP) | 2019-08-01 | — | — | US | disclosed |
| US-10202470-B2 | Polymerizable composition and optically anisotropic body using same | DIC CORPORATION (JP) | 2019-02-12 | — | — | US | disclosed |
| US-8019550-B2 | Drug discovery method | Keddem Bioscience Ltd. (IL) | 2011-09-13 | — | — | US | disclosed |
| US-8019550-B2 | Drug discovery method | Keddem Bioscience Ltd. (IL) | 2011-09-13 | — | — | US | disclosed |
| EP-1540329-A4 | DRUG DISCOVERY METHOD | KEDDEM BIO SCIENCE LTD (IL) | 2009-06-10 | — | — | EP | disclosed |
| US-20050277117-A1 | Drug discovery method | KEDDEM BIO-SCIENCE LTD. (IL) | 2005-12-15 | — | — | US | disclosed |
| EP-1540329-A1 | DRUG DISCOVERY METHOD | KEDDEM BIO-SCIENCE LTD. (IL) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004010136-A1 | DRUG DISCOVERY METHOD | KEDDEM BIO-SCIENCE LTD. (IL) | 2004-01-29 | — | — | WO | disclosed |
| US-6492087-B1 | PHOTOACID LABILE UNIT ATTACHED TO SUCH AS POLYHYDROXYSTYRENE THAT CAN GENERATE MULTIPLE ANIONS OR ACIDIC GROUPS SUCH AS HYDROXYL, PARTICULARLY PHENOLIC, COMPOUNDS VIA A DEPROTECTION REACTION WITHOUT RELEASING VOLATILE COMPONENTS | SHIPLEY COMPANY, L.L.C. | 2002-12-10 | — | — | US | disclosed |
| EP-1031878-A1 | Novel polymers and photoresist compositions comprising same | Shipley Company LLC (US) | 2000-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927263-B2 | Polymerizable composition and optically anisotropic body produced using the same | CRYAA, IK, LCP1 | ABCG2 3656/4885ITGB2 262/4885ICAM1 1193/4885 |
| US-10723952-B2 | Polymerizable compound and optically anisotropic body | SMC4, SMCHD1, PHOSPHO1 | ABCG2 2480/4885ITGB2 3328/4885ICAM1 3692/4885 |
| US-20190264034-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY PRODUCED USING THE SAME | CRYAA, IK, LCP1 | ABCG2 3656/4885ITGB2 262/4885ICAM1 1193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.