Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252376 | 0.82 | CLK4 (0.31) | — | |
| SCHEMBL24252212 | 0.76 | CTDSP1 (0.33) | ALDH1A1THRBMAPK1POLB | |
| SCHEMBL24252406 | 0.76 | CYP2D6 (0.37) | — | |
| SCHEMBL8871735 | 0.71 | ALDH1A1 (0.38) | ALDH1A1THRBMAPK1POLB | |
| SCHEMBL24252214 | 0.71 | — | — | |
| SCHEMBL12031151 | 0.69 | ALDH1A1 (0.34) | ALDH1A1THRBMAPK1POLB | |
| SCHEMBL13952783 | 0.69 | ALDH1A1 (0.34) | ALDH1A1THRBMAPK1POLB | |
| SCHEMBL24252372 | 0.69 | ALDH1A1 (0.33) | ALDH1A1MAPK1 | |
| SCHEMBL24252371 | 0.69 | — | — | |
| SCHEMBL16381859 | 0.64 | ALDH1A1 (0.33) | ALDH1A1THRBMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022034203-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | WO | disclosed |