SCHEMBL24252376

SCHEMBL24252376

COC1OC(=O)C=C1c1ncccn1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CLK4 Q9HAZ1 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24252213 0.82 ALDH1A1 (0.33)
SCHEMBL24252214 0.74
SCHEMBL24252375 0.73 CYP2C8 (0.31)
SCHEMBL24252411 0.73 CYP2D6 (0.33)
SCHEMBL24252372 0.73 ALDH1A1 (0.33)
SCHEMBL24252371 0.72
SCHEMBL24252378 0.66 LMNA (0.35)
SCHEMBL24252377 0.65 HRH3 (0.35) KDM4E
SCHEMBL24252219 0.64 PRKDC (0.33) KDM4E
SCHEMBL6854316 0.58 CLK4 (0.45) CLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022034203-A1 PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2022-02-17 WO disclosed