Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252411 | 0.85 | CYP2D6 (0.33) | CYP2D6LMNAGAAGSK3B | |
| SCHEMBL24252212 | 0.76 | CTDSP1 (0.33) | — | |
| SCHEMBL24252213 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL24252410 | 0.75 | CCNT1 (0.33) | CYP2D6LMNAGAAGSK3B | |
| SCHEMBL24252409 | 0.74 | CCNT1 (0.33) | LMNAGAAGSK3B | |
| SCHEMBL24252408 | 0.73 | GSK3B (0.33) | CYP2D6LMNAGAAGSK3B | |
| SCHEMBL24252414 | 0.68 | GSK3B (0.38) | CYP2D6GSK3B | |
| SCHEMBL24252407 | 0.67 | GSK3B (0.40) | CYP2D6GSK3B | |
| SCHEMBL24252413 | 0.66 | GSK3B (0.43) | CYP2D6GSK3B | |
| SCHEMBL8871735 | 0.66 | ALDH1A1 (0.38) | LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022034203-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | WO | disclosed |